Alastair Buchan is Professor of Stroke Medicine at the University of Oxford and will be collaborating with the Center for Stroke Research at the Charité - Universitätsmedizin, with fellow researchers at the NeuroCure excellence cluster, and with neurologist and Einstein Junior Fellow Philipp Mergenthaler. The stroke expert's group will research novel neuroprotective therapies and develop treatment strategies and drugs to prevent the death of additional nerve cells when blood flow is restricted in the brain. The most tried and tested method when this occurs is hypothermia, which involves artificially lowering body temperature. Alastair Buchan and his colleagues based at the Charité - Universitätsmedizin will investigate which molecular mechanisms play a role in hypothermic neuroprotection during stroke treatment, and how this is related to glucose metabolism in the brain. A further aim of Alastair Buchan's fellowship is to establish an international academy for the next generation of clinical scientists in neurological vascular research and to step up collaboration between top researchers from Oxford and Berlin.