After completing his doctorate in biology at Heinrich-Heine-Universität Düsseldorf, Sameer Singh spent several years as a postdoc conducting research at the Albert Einstein College of Medicine and at the Rockefeller University in New York. Since 2022, he has been based at Charité, where, as an Einstein Independent Researcher, he will be working with Christian Spahn, Director of the Institute of Medical Physics and Biophysics at Charité, to investigate ribosomopathies in greater depth. This group of rare diseases can be traced back to mutations in ribosomal proteins that cause ribosome dysfunction. Ribosomes are RNA-protein complexes that are present in all living organisms. They read the protein sequence encoded in the mRNA and produce the corresponding proteins. The aim of the project is to visualize the ribosome biosynthesis process with the help of cutting-edge imaging methods to explain how exactly defective ribosome production leads to ribosomopathies and, in the long term, how treatment options can be developed.